If you love the comforting charm of classic comfort foods, you’re going to absolutely fall head over heels for this Mac and Cheese Meatloaf Casserole Recipe. It’s a wonderfully indulgent fusion of two all-time favorites—creamy mac and cheese and hearty meatloaf—layered together in one irresistible casserole that’s perfect for family dinners or casual get-togethers. This dish brings together the rich, cheesy goodness of mac and cheese with the savory, satisfying texture of meatloaf, resulting in a meal that’s everybody-pleasing and surprisingly simple to make. Trust me, once you try this Mac and Cheese Meatloaf Casserole Recipe, it’s going to become your new go-to comfort food classic!

Ingredients You’ll Need

Gathering simple, wholesome ingredients is key to creating the perfect balance of flavors and textures in this recipe. Each component plays an essential role, from the tender ground beef bringing savory depth, to the creamy cheddar cheese offering that signature mac and cheese richness and beautiful golden color on top.

  • 1 lb ground beef: Choose fresh ground beef for a juicy, flavorful base that makes the meatloaf irresistible.
  • 1/2 cup diced onion: Adds a sweet and aromatic layer of flavor that complements the beef perfectly.
  • 1/2 cup breadcrumbs: These help hold the meatloaf together while keeping it tender and moist.
  • 1 large egg: Acts as a binder to keep the meat and other ingredients combined beautifully.
  • 2 cups macaroni, uncooked: The perfect pasta shape to soak up all that luscious cheese sauce.
  • 2 cups shredded cheddar cheese: Be sure to use sharp cheddar for the best cheesy flavor that melts perfectly.
  • 4 cups milk (divided): Creamy milk is essential for making the cheese sauce silky smooth and dreamy.
  • 2 tbsp butter: Adds richness and helps create the roux for the cheese sauce’s thick texture.
  • Various seasonings (salt, pepper, paprika, dry mustard): These elevate the dish with layers of savory warmth and a slight tang, rounding out every bite.

How to Make Mac and Cheese Meatloaf Casserole Recipe

Step 1: Preheat Your Oven

Start by heating your oven to 350°F (175°C). This ensures that your meatloaf starts cooking at the right temperature, locking in flavor and moisture from the moment it goes into the oven.

Step 2: Prepare the Meatloaf Base

In a large mixing bowl, blend together the ground beef, diced onion, breadcrumbs, egg, some milk, salt, and pepper. This mixture is the foundation of your meatloaf, where every ingredient mingles to create that perfect balance of taste and texture. Once combined, firmly press the mixture into a greased 9×13-inch baking dish, shaping it evenly.

Step 3: Bake the Meatloaf

Pop the dish into the oven and bake the meatloaf for 20 minutes. This initial bake firms up the meat, helping it hold its shape when you add the creamy mac and cheese layer later.

Step 4: Cook the Macaroni

While the meatloaf bakes, bring a pot of salted water to a boil and cook the macaroni according to the package instructions. Once tender, drain the pasta thoroughly but don’t overcook it. The macaroni needs to be just right to soak up the cheese sauce without becoming mushy.

Step 5: Make the Cheese Sauce

In a saucepan over medium heat, melt the butter. Stir in flour to create a roux, then gradually whisk in 2 cups of milk until the sauce thickens into a velvety consistency. Add the seasonings—salt, pepper, paprika, and dry mustard—to infuse the sauce with extra zing. Stir in 1½ cups of shredded cheddar cheese until melted and silky smooth. This sauce is pure comfort and the heart of the ‘cheese’ in this Mac and Cheese Meatloaf Casserole Recipe.

Step 6: Combine Macaroni and Cheese Sauce

Mix the cooked macaroni into the cheese sauce until every noodle is luxuriously coated. Then, pour this cheesy pasta layer evenly over the partially baked meatloaf in your baking dish. Finish by sprinkling the remaining ½ cup of shredded cheese on top to get that ooey-gooey golden crust.

Step 7: Bake Until Bubbly

Return the casserole to the oven and bake for an additional 25 minutes. This finishes cooking the meatloaf through and melts the cheese topping to bubbly, golden perfection. The aroma while it’s baking is pure heaven!

How to Serve Mac and Cheese Meatloaf Casserole Recipe

Garnishes

To add a pop of color and fresh contrast, sprinkle some finely chopped fresh parsley or chives just before serving. This not only brightens the plate but also adds a fragrant, herbaceous note that cuts through the richness deliciously.

Side Dishes

Because this casserole is so rich and hearty, pairing it with lighter sides works beautifully. A crisp green salad with a tangy vinaigrette or roasted seasonal vegetables brings balance to your meal without competing with the bold flavors of the Mac and Cheese Meatloaf Casserole Recipe.

Creative Ways to Present

For an eye-catching presentation, serve individual portions in small ramekins or cast-iron skillets to make everyone feel extra special. Alternatively, garnish with a dusting of smoked paprika or a drizzle of hot sauce for a fun twist that amps up the flavor profile.

Make Ahead and Storage

Storing Leftovers

Leftover Mac and Cheese Meatloaf Casserole Recipe keeps really well in the fridge. Store tightly covered in an airtight container, ideally within two hours of cooking, and enjoy it within 3 to 4 days for the best quality and safety.

Freezing

This casserole freezes wonderfully, making it a fantastic make-ahead meal. Wrap it tightly in plastic wrap followed by foil, or place individual portions in freezer-safe containers. Freeze for up to three months to preserve freshness and flavor.

Reheating

When you’re ready to enjoy your leftovers, thaw frozen portions overnight in the fridge if possible. Reheat in the oven at 350°F until warmed through to maintain that delicious texture and flavor. Microwaving works for a quick fix but may sacrifice some crispness on top.

FAQs

Can I use ground turkey instead of beef in this recipe?

Absolutely! Ground turkey is a leaner option that works well in this casserole. Just keep in mind it may need a bit more seasoning to boost the flavor, as turkey is milder than beef.

What type of cheese is best for the mac and cheese sauce?

Sharp cheddar is my favorite here because it melts smoothly and packs a punch of flavor. However, you can mix in mozzarella or gouda for a milder, creamier sauce if you prefer.

Can I prepare this casserole ahead of time and bake it later?

Yes! Assemble the casserole completely and cover it tightly with foil or plastic wrap, then refrigerate for up to 24 hours before baking. Just add a few extra minutes to the bake time if baking from cold.

Is there a way to make this recipe gluten-free?

Definitely. Substitute regular macaroni with gluten-free pasta and use gluten-free breadcrumbs or crushed gluten-free crackers. Also, check that your seasonings don’t contain hidden gluten.

How can I make this recipe spicier?

Add a pinch of cayenne pepper to the cheese sauce or sprinkle some red pepper flakes on top before baking for a subtle heat that complements the savory flavors nicely.

Final Thoughts

This Mac and Cheese Meatloaf Casserole Recipe is a total knockout when you want to bring warmth, comfort, and a bit of wow-factor to your dinner table. It’s simple enough for weeknights but impressive enough to serve guests, blending creamy and hearty in every single delicious bite. Don’t hesitate to make this dish your own and enjoy the joyful smiles it’s bound to inspire!

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Mac and Cheese Meatloaf Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4 from 47 reviews
  • Author: admin
  • Prep Time: 20 minutes
  • Cook Time: 45 minutes
  • Total Time: 1 hour 5 minutes
  • Yield: Serves 8
  • Category: Casserole
  • Method: Baking
  • Cuisine: American

Description

This Mac and Cheese Meatloaf Casserole combines hearty meatloaf with creamy macaroni and cheese to create a comforting and satisfying one-dish meal perfect for family dinners. Ground beef is mixed with onions, breadcrumbs, and seasonings, baked partially before being topped with a rich and cheesy macaroni sauce and baked again to bubbly perfection.


Ingredients

Scale

Meatloaf

  • 1 lb ground beef
  • 1/2 cup diced onion
  • 1/2 cup breadcrumbs
  • 1 large egg
  • 2 cups milk (divided)
  • Salt, to taste
  • Black pepper, to taste

Macaroni and Cheese Sauce

  • 2 cups uncooked macaroni
  • 2 tbsp butter
  • 2 tbsp all-purpose flour
  • 2 cups milk
  • 1 1/2 cups shredded cheddar cheese
  • 1/2 tsp paprika
  • 1/2 tsp dry mustard
  • Salt and pepper, to taste
  • 1/2 cup shredded cheddar cheese (for topping)


Instructions

  1. Preheat Oven: Preheat your oven to 350°F (175°C) to prepare for baking the casserole.
  2. Prepare Meatloaf Mixture: In a mixing bowl, combine the ground beef, diced onion, breadcrumbs, egg, 2 cups of milk, salt, and pepper. Mix until evenly combined and press the mixture into a greased 9×13-inch baking dish.
  3. Bake Meatloaf Base: Bake the meatloaf mixture for 20 minutes to set the base before adding the macaroni and cheese topping.
  4. Cook Macaroni: Meanwhile, cook the macaroni according to the package instructions until al dente. Drain and set aside.
  5. Make Cheese Sauce: In a saucepan over medium heat, melt butter. Stir in flour and cook for about 1 minute to form a roux. Gradually whisk in 2 cups of milk, stirring constantly until the sauce thickens. Add paprika, dry mustard, salt, pepper, and 1 1/2 cups shredded cheddar cheese. Stir until the cheese is completely melted.
  6. Combine Macaroni and Cheese Sauce: Mix the cooked macaroni into the cheese sauce until well coated.
  7. Assemble Casserole: Pour the macaroni and cheese over the partially baked meatloaf in the baking dish. Sprinkle the remaining 1/2 cup shredded cheddar cheese evenly on top.
  8. Final Bake: Return the casserole to the oven and bake for an additional 25 minutes or until bubbly and the top is golden brown.

Notes

  • You can substitute ground beef with ground turkey or chicken for a leaner option.
  • Use gluten-free breadcrumbs to make this recipe gluten-free if needed.
  • For extra flavor, consider adding garlic powder or Worcestershire sauce to the meatloaf mixture.
  • Let the casserole rest for 5 minutes before serving for easier slicing.

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